XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (II)

To summarize the main new findings in clinical research on MS. Content and Conclusions: The immunological changes throughout life and in response to MS treatments were analyzed. The impact of aging was also discussed, along with new developments related to symptomatic treatments, physical exercise, fatigue, and sleep disorders. Emphasis was placed on addressing ongoing challenges in measuring therapeutic failure and managing treatments for secondary progressive MS. Additionally, data from registries and real-world studies were presented, including new analyses on cladribine, highlighting the need to collect safety information. Regarding immune reconstitution therapies, mechanisms of action and the immune system's reconstitution process after treatment were explored. Finally, regarding therapeutic innovations, the first results from chimeric antigen receptor (CAR)-T cell therapy studies in MS were reported, representing a promising advancement in disease management.

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Publication Details

Journal
Revista de Neurología
Published
2026-01-21
DOI
https://doi.org/10.31083/rn39228
Primary Topic
Multiple Sclerosis Research Studies
Type
article
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article

XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (II)

A M Alonso, Luis F. Brieva, Óscar Fernández Fernández, José María Prieto et al.
Revista de Neurología
Multiple Sclerosis Research Studies
article

XVII Post-ECTRIMS Meeting: Review of the New Developments Presented at the 2024 ECTRIMS Congress (II)

A M Alonso, Luis F. Brieva, Óscar Fernández Fernández, José María Prieto, Miguel Ángel Hernández, Ana B. Caminero, E. Moral, Sara Llufriu, Virginia Meca-Lallana, Eduardo Agüera, Yolanda Aladro, Andreu Vilaseca, José E. Meca-Lallana, Carmen Calles, Miguel Llaneza, Lamberto Landete, Lucía Romero-Pinel, Sara Eichau, Rafael Arroyo, Adrián Arés
article en

Abstract

To summarize the main new findings in clinical research on MS. Content and Conclusions: The immunological changes throughout life and in response to MS treatments were analyzed. The impact of aging was also discussed, along with new developments related to symptomatic treatments, physical exercise, fatigue, and sleep disorders. Emphasis was placed on addressing ongoing challenges in measuring therapeutic failure and managing treatments for secondary progressive MS. Additionally, data from registries and real-world studies were presented, including new analyses on cladribine, highlighting the need to collect safety information. Regarding immune reconstitution therapies, mechanisms of action and the immune system's reconstitution process after treatment were explored. Finally, regarding therapeutic innovations, the first results from chimeric antigen receptor (CAR)-T cell therapy studies in MS were reported, representing a promising advancement in disease management.

Revista de NeurologíaVol. 81(1)
Catholic University of Ávila (ES), Bellvitge University Hospital (ES), Hospital Universitari Arnau de Vilanova (ES), Hospital Clínico San Carlos (ES), Hospital Universitario Nuestra Señora de Candelaria (ES), Hospital Universitario Virgen Macarena (ES), Spanish Multiple Sclerosis Network (ES), Complejo Hospitalario Universitario de Santiago (ES), Hospital Universitario de Getafe (ES), Hospital Regional Universitario de Málaga (ES), Hospital Universitario Quirónsalud Madrid (ES), Hospital Clínic de Barcelona (ES), Hospital Universitario Reina Sofía (ES), Hospital Universitario Doctor Peset (ES), Vall d'Hebron Hospital Universitari (ES), Hospital Universitario de La Princesa (ES), Hospital de Sant Joan Despí Moisès Broggi (ES), Hospital Universitario Central de Asturias (ES), Hospital de Cruces (ES), Donostiako Unibertsitate Ospitalea (ES), Instituto de Investigación Sanitaria de Santiago (ES), Hospital Universitario Virgen de la Arrixaca (ES), Hospital Universitario Son Espases (ES), Hospital Universitario Ramón y Cajal (ES), Complejo Asistencial Universitario de Palencia (ES), Instituto de Investigación Biomédica de Málaga (ES)
Good health and well-being
Openalex Percentile: Top 74%
Multiple Sclerosis Research Studies
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