Hypoperfusion on Early MRI Despite Successful Thrombectomy: A Prospective Imaging and Inflammatory Biomarkers Study
Early perfusion deficits after EVT most often reflect residual distal emboli. Macrovascular hypoperfusion was not associated with inflammatory biomarkers. Nevertheless, our integrated imaging and biomarker strategy lays the foundation for future mechanistic and therapeutic studies targeting microvascular reperfusion failure.
Authors
- Quentin Varnier
- Thomas Checkouri (ORCID: https://orcid.org/0000-0003-0746-6383)
- Thibaut Roux
- Pierre-Henri Lefèvre (ORCID: https://orcid.org/0000-0002-6196-3869)
- François-Louis Collemiche (ORCID: https://orcid.org/0000-0002-1494-1704)
- V. Costalat
- Nicola Andrea Marchi (ORCID: https://orcid.org/0000-0002-7809-4399)
- Julien Labreuche
- Emmanuelle Le Bars
- Marine Blaquière
- Xavier Ayrignac
- Lucas Corti
- Pierre Seners
- Cyril Dargazanli
- Federico Cagnazzo
- Jean-Claude Baron
- Michael Mlynash
- Maarten G. Lansberg
- Jeremy J. Heit
- Marinette Moynier
- Adrien ter Schiphorst
- Gregory W. Albers
- Soren Christensen
- Isabelle Mourand
- Caroline Arquizan
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Palo Alto University (US)
- Université de Montpellier (FR)
- Université Paris Cité (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Centre National pour la Recherche Scientifique et Technique (CNRST) (MA)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Hôpital Gui de Chauliac (FR)
- Fondation Ophtalmologique Adolphe de Rothschild (FR)
- Institut de Psychiatrie et Neurosciences de Paris (FR)
- Stanford Medicine (US)
- FHU Neurovasc (FR)
- Institut de Génomique Fonctionnelle (FR)
- Stanford University (US)
Publication Details
- Journal
- Stroke
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1161/strokeaha.125.052873
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00