Association between reproductive factors and fibromyalgia: a cross-sectional analysis of female health profiles

Grand multiparity was independently associated with fibromyalgia, suggesting that cumulative hormonal and physiological stress from multiple pregnancies may contribute to chronic pain susceptibility. No association was found between age at first pregnancy and FM. Larger, longitudinal studies are warranted to clarify causal pathways between reproductive history and FM pathogenesis.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2025-10-02
DOI
https://doi.org/10.55563/clinexprheumatol/pg971k
Primary Topic
Pregnancy-related medical research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between reproductive factors and fibromyalgia: a cross-sectional analysis of female health profiles

Duygu Kurtuluş, Selma Selma Dağci, Behzat CAN, Kevser Arkan et al.
Clinical and Experimental Rheumatology
Pregnancy-related medical research
article

Association between reproductive factors and fibromyalgia: a cross-sectional analysis of female health profiles

Duygu Kurtuluş, Selma Selma Dağci, Behzat CAN, Kevser Arkan, Sedat Akgol
article en

Abstract

Grand multiparity was independently associated with fibromyalgia, suggesting that cumulative hormonal and physiological stress from multiple pregnancies may contribute to chronic pain susceptibility. No association was found between age at first pregnancy and FM. Larger, longitudinal studies are warranted to clarify causal pathways between reproductive history and FM pathogenesis.

Clinical and Experimental Rheumatology
Ümraniye Eğitim ve Araştırma Hastanesi (TR), Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi (TR), Istanbul Eye Hospital (TR), Australia New Zealand Gynaecological Oncology Group (AU)
Openalex Percentile: Top 23%
Pregnancy-related medical research
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