Intraperitoneal Paclitaxel-Induced Eosinophil Recruitment as a Potential Mediator of Tumor Response in Peritoneal Metastases from Gastric Cancer
IP PTX promotes the recruitment and activation of eosinophils with potent antitumor activity in the peritoneal cavity. Early post-treatment abdominal eosinophilia is a robust prognostic biomarker and may represent a promising therapeutic target to enhance the efficacy of IP chemotherapy in patients with PM from GC.
Authors
- Kentaro Kurashina (ORCID: https://orcid.org/0000-0003-4034-9883)
- Hirofumi Sonoda (ORCID: https://orcid.org/0000-0003-3353-1783)
- Shiro Matsumoto (ORCID: https://orcid.org/0000-0003-1028-5532)
- Hiroharu Yamashita (ORCID: https://orcid.org/0000-0002-9468-3716)
- Misaki Matsumiya
- K. Takahashi
- Hideyo Miyato
- Joji Kitayama
- Shin Saito
- Yoshinori Hosoya
- Naohiro Sata
- Hironori Yamaguchi
- Hideyuki Ohzawa
Institutions
- Jichi Medical University (JP)
- Murayama Medical Center (JP)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1245/s10434-025-19075-x
- Citations
- 2
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 78.29