Genetic determinants of HIV-1 elite control

The genetic architecture of HIV-1 elite control is more complex than previously appreciated. The field has moved beyond HLA to uncover new, ancestry-specific pathways, explore multiple biological variables, and confront the critical disconnect between controlling viremia and eliminating the latent reservoir.

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Publication Details

Journal
Current Opinion in HIV and AIDS
Published
2026-01-29
DOI
https://doi.org/10.1097/coh.0000000000001019
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic determinants of HIV-1 elite control

Jacques Fellay, Christian W. Thorball, Barry Ryan
Current Opinion in HIV and AIDS
HIV Research and Treatment
article

Genetic determinants of HIV-1 elite control

Jacques Fellay, Christian W. Thorball, Barry Ryan
article en

Abstract

The genetic architecture of HIV-1 elite control is more complex than previously appreciated. The field has moved beyond HLA to uncover new, ancestry-specific pathways, explore multiple biological variables, and confront the critical disconnect between controlling viremia and eliminating the latent reservoir.

Current Opinion in HIV and AIDS
SIB Swiss Institute of Bioinformatics (CH), University of Lausanne (CH)
Good health and well-being
Openalex Percentile: Top 74%
HIV Research and Treatment
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Genetic determinants of HIV-1 elite control — Jacques Fellay, Christian W. Thorball, et al. · Current Opinion in HIV and AIDS (2026) | TGRS Research Map | TGRS