Bidirectional nexus between metabolic disease and aortic valve calcification: from pathogenic mechanisms to integrated multimorbidity management
Future management strategies must transition toward early, multi-disease co-governance strategies. At the same time, targeted drugs will be developed for specific pathways on this axis, surpassing the current treatment status of relying solely on valve replacement surgery.
Authors
- Xinyue Wang (ORCID: https://orcid.org/0000-0002-9206-0021)
- Jia Xu (ORCID: https://orcid.org/0000-0002-8849-2462)
- Mincheng Yu
- Yi Liu
- Jingzheng Chen
- Zhongqun Wang
Institutions
- Jiangsu University (CN)
- Affiliated Hospital of Jiangsu University (CN)
Publication Details
- Journal
- Expert Opinion on Therapeutic Targets
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1080/14728222.2026.2625100
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00