Baseline D-dimer as a predictor of immune checkpoint inhibitor efficacy in cancer

Baseline D-dimer is a readily measurable, cost-effective biomarker that predicts inferior outcomes in patients receiving ICIs. Its integration into clinical workflows may aid patient stratification and guide treatment decisions. Prospective multicenter studies are warranted to validate cutoff thresholds and further define its utility in optimizing immunotherapy efficacy.

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Publication Details

Journal
Annals of Medicine
Published
2026-01-28
DOI
https://doi.org/10.1080/07853890.2026.2620195
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Baseline D-dimer as a predictor of immune checkpoint inhibitor efficacy in cancer

Jie Zha, W Zhang, Meimei Hu, Fan Li
Annals of Medicine
Cancer Immunotherapy and Biomarkers
article

Baseline D-dimer as a predictor of immune checkpoint inhibitor efficacy in cancer

Jie Zha, W Zhang, Meimei Hu, Fan Li
article en

Abstract

Baseline D-dimer is a readily measurable, cost-effective biomarker that predicts inferior outcomes in patients receiving ICIs. Its integration into clinical workflows may aid patient stratification and guide treatment decisions. Prospective multicenter studies are warranted to validate cutoff thresholds and further define its utility in optimizing immunotherapy efficacy.

Annals of MedicineVol. 58(1)
Anqing Normal University (CN)
Openalex Percentile: Top 74%
Cancer Immunotherapy and Biomarkers
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Baseline D-dimer as a predictor of immune checkpoint inhibitor efficacy in cancer — Jie Zha, W Zhang, et al. · Annals of Medicine (2026) | TGRS Research Map | TGRS