Establishing oncological safety of autologous fat transfer for total breast reconstruction: Results from the multicentre BREAST-I and BREAST-II trials
In this pooled multicentre cohort with long-term follow-up, AFT for total breast reconstruction after mastectomy did not negatively affect mortality compared with national registry controls. These results support the oncological safety of AFT as a reconstructive technique. Future research should include larger cohorts and assess disease-free survival.
Authors
- Chantal M. Mouës
- Xavier H.A. Keuter (ORCID: https://orcid.org/0000-0001-8302-5657)
- Liang Tan (ORCID: https://orcid.org/0000-0002-9014-5371)
- Pauline M. Huizinga
- Caroline Driessen (ORCID: https://orcid.org/0000-0002-8395-527X)
- Ute Schmidbauer
- Naomi van Hout
- Hinne A. Rakhorst (ORCID: https://orcid.org/0000-0002-1663-6092)
- Corinne Schouten
- Jan-Maerten Smit
- Mikko Larsen
- Esther M. Heuts
- Wessel B.W. van der Venne
- Roos Michiels
- Henriëtte C. Kroese
- Marjolein M. de Lange
- Jamilla L.M. Wederfoort
- Sander M.J. Van Kuijk
- An E.K. Deliaert
- Thijs de Wit
- Kim M.E. Wehrens
- Juliette E. Hommes
- Rose J.T.R Rhemrev
- Jan Maerten Smit
- Vivianne C.G. Tjan-Heijnen
- Sander S.J. Schop
- Todor K. Krastev
- René R.W.J. Van der Hulst
- Patrick I. Fernandinus
- Danielle Derks
- Maud E.P. Rijkx
- Andrzej A.Piatkowski de Grzymala
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Department of Health (TW)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1016/j.ejso.2026.111417
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00