Rates and determinants of incident lacunes: A systematic review and meta-analysis

Incident lacune rates vary substantially across populations and are strongly influenced by baseline lacune burden and vascular risk factors. These findings provide context for population selection and sample size considerations in studies using incident lacunes as an imaging outcome.

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Publication Details

Journal
International Journal of Stroke
Published
2026-01-28
DOI
https://doi.org/10.1177/17474930261421046
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Rates and determinants of incident lacunes: A systematic review and meta-analysis

Fei Han, Joanna Wardlaw
International Journal of Stroke
Dementia and Cognitive Impairment Research
article

Rates and determinants of incident lacunes: A systematic review and meta-analysis

Fei Han, Joanna Wardlaw
article en

Abstract

Incident lacune rates vary substantially across populations and are strongly influenced by baseline lacune burden and vascular risk factors. These findings provide context for population selection and sample size considerations in studies using incident lacunes as an imaging outcome.

International Journal of Stroke
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), UK Dementia Research Institute (GB), University of Edinburgh (GB)
Openalex Percentile: Top 74%
Dementia and Cognitive Impairment Research
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