Sex differences in the prevalence and risk factors for aortic valve calcification in the general population

Male sex was independently associated with AVC, and the prevalence of AVC was nearly twice as high in men as in women. Traditional cardiovascular risk factors, including lipoprotein(a), hyperlipidaemia, hypertension and smoking, were associated with AVC, with similar associations between sexes, except for BMI, which was associated with AVC in men but not in women.

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Publication Details

Journal
Heart
Published
2026-01-29
DOI
https://doi.org/10.1136/heartjnl-2025-326468
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

Sex differences in the prevalence and risk factors for aortic valve calcification in the general population

Athena Adeli, C J Östgren, Anne Wang, Stefan Söderberg et al.
Heart
Cardiac Valve Diseases and Treatments
article

Sex differences in the prevalence and risk factors for aortic valve calcification in the general population

Athena Adeli, C J Östgren, Anne Wang, Stefan Söderberg, A Blomberg, Professor Eva Swahn, Tomas Jernberg, Bahira Shahim, Gunnar Engström, Göran Bergström, Magnus Settergren, Lars Lind
article en

Abstract

Male sex was independently associated with AVC, and the prevalence of AVC was nearly twice as high in men as in women. Traditional cardiovascular risk factors, including lipoprotein(a), hyperlipidaemia, hypertension and smoking, were associated with AVC, with similar associations between sexes, except for BMI, which was associated with AVC in men but not in women.

Heart
Linköping University (SE), Uppsala University (SE), Karolinska University Hospital (SE), Lund University (SE), Karolinska Institutet (SE), University of Gothenburg (SE), Umeå University (SE)
Good health and well-being
Openalex Percentile: Top 75%
Cardiac Valve Diseases and Treatments
DOIOpen Access PDFOpenAlex
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Sex differences in the prevalence and risk factors for aortic valve calcification in the general population — Athena Adeli, C J Östgren, et al. · Heart (2026) | TGRS Research Map | TGRS