Aquaporin‐1 differentiates intrahepatic cholangiocarcinoma from liver metastases of pancreatic ductal adenocarcinoma
AQP1 is a novel biliary biomarker which has been shown to outperform other biliary biomarkers. The main diagnostic scenario in which AQP1 staining should be used is to distinguish iCCA from mPDAC. Furthermore, differential diagnosis between eCCA and PDAC in surgical specimens and between PDAC and CP in needle biopsies should be considered.
Authors
- Leoncini Giuseppe
- Ronchetti Simona
- D V Michele
- Barella Marco
- Mazzaferro Vincenzo
- Gentili Marco
- Bodini Beatrice
- Cari Luigi
Institutions
- University of Milan (IT)
- University of Perugia (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Publication Details
- Journal
- Histopathology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1111/his.70108
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00