Clinical Outcomes of Dantrolene in Neuroleptic Malignant Syndrome: A Nationwide Retrospective Study

In the largest study of NMS to date, early initiation of dantrolene was associated with higher in-hospital mortality and prolonged ICU/hospital stay. These findings suggest that routine use of dantrolene in NMS should be reevaluated.

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Publication Details

Journal
Acta Psychiatrica Scandinavica
Published
2026-01-29
DOI
https://doi.org/10.1111/acps.70073
Primary Topic
Electroconvulsive Therapy Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical Outcomes of Dantrolene in Neuroleptic Malignant Syndrome: A Nationwide Retrospective Study

Atsushi Senda, Koji Morishita, Akira Suekane, Kiyohide Fushimi
Acta Psychiatrica Scandinavica
Electroconvulsive Therapy Studies
article

Clinical Outcomes of Dantrolene in Neuroleptic Malignant Syndrome: A Nationwide Retrospective Study

Atsushi Senda, Koji Morishita, Akira Suekane, Kiyohide Fushimi
article en

Abstract

In the largest study of NMS to date, early initiation of dantrolene was associated with higher in-hospital mortality and prolonged ICU/hospital stay. These findings suggest that routine use of dantrolene in NMS should be reevaluated.

Acta Psychiatrica Scandinavica
Tokyo Medical and Dental University (JP)
Good health and well-being
Openalex Percentile: Top 74%
Electroconvulsive Therapy Studies
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Clinical Outcomes of Dantrolene in Neuroleptic Malignant Syndrome: A Nationwide Retrospective Study — Atsushi Senda, Koji Morishita, et al. · Acta Psychiatrica Scandinavica (2026) | TGRS Research Map | TGRS