Behavioral Risk Factors and Seroprevalence for Human Papillomavirus in Sinonasal Carcinoma: A Multi‐Institutional Case–Control Study

HPV-SNC exhibits distinct serologic features without clear behavioral risk factors. The protective association of tonsillectomy suggests lymphoid tissue may play a role in HPV-associated sinonasal oncogenesis. In contrast, the absence of identifiable risk factors for HPV-independent SNC highlights the need for further etiologic studies.

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Publication Details

Journal
Head & Neck
Published
2026-01-29
DOI
https://doi.org/10.1002/hed.70171
Primary Topic
Head and Neck Surgical Oncology
Type
article
Field-Weighted Citation Impact
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article

Behavioral Risk Factors and Seroprevalence for Human Papillomavirus in Sinonasal Carcinoma: A Multi‐Institutional Case–Control Study

Raymond J. So, T Waterboer, Melina J. Windon, Ved Tanavde et al.
Head & Neck
Head and Neck Surgical Oncology
article

Behavioral Risk Factors and Seroprevalence for Human Papillomavirus in Sinonasal Carcinoma: A Multi‐Institutional Case–Control Study

Raymond J. So, T Waterboer, Melina J. Windon, Ved Tanavde, Birgitta E. Michels, Anuj Tharakan, Sophia S Jung, Gypsamber D’Souza, David W. Jang, Nyall R. London, Fahad Alkahtani, Zubair Khan, Jordan Smith, Ralph Abi Hachem, Tanvir Queraishi
article en

Abstract

HPV-SNC exhibits distinct serologic features without clear behavioral risk factors. The protective association of tonsillectomy suggests lymphoid tissue may play a role in HPV-associated sinonasal oncogenesis. In contrast, the absence of identifiable risk factors for HPV-independent SNC highlights the need for further etiologic studies.

Head & Neck
University of Kentucky (US), Johns Hopkins University (US), Duke University (US), German Cancer Research Center (DE), Heidelberg University (DE), Johns Hopkins Medicine (US), National Cancer Institute (US), Duke University Hospital (US)
Good health and well-being
Openalex Percentile: Top 74%
Head and Neck Surgical Oncology
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