Association between depression during pregnancy and preterm birth: Results from population cohorts and mouse experimental models

This study demonstrates a significant association between prenatal depressive symptoms and an increased risk of preterm birth in a Chinese multiethnic cohort. Experimental findings from a mouse model further suggest a potential contributory role of depression to PTB. These results underscore the importance of screening for and addressing maternal mental health during pregnancy. Future research should focus on underlying mechanisms and intervention strategies to mitigate this risk.