Neuroprotective Herbs Associated with Parkinson’s and Alzheimer’s Disease

There is currently no treatment for Parkinson's (PD) and Alzheimer's (AD) diseases, and medications that target the blockage of amyloid plaque cascades appear to be the most promising for preventing these diseases. However, it is believed that consuming natural antioxidants, particularly phytochemicals such as phenolic compounds, may help the treatment process for neurodegenerative illnesses. Phenolic substances such as phenolic acids, polyphenols, and flavonoids have been shown to have antioxidant properties in plants and are thought to have a similar impact in humans. This review provides an analysis of the current landscape of PD and AD pathophysiology, paying particular attention to phytochemical-based therapeutic, preventive, and management strategies using disclosed herb candidates in in vivo/vitro studies. We also highlight the herb-derived components that have recently been identified for their effects in the treatment of PD/AD to provide a review and perspectives for the development of the next generation of drugs and preparations for the treatment of PD/AD.

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Publication Details

Journal
Nutrients
Published
2026-01-29
DOI
https://doi.org/10.3390/nu18030439
Primary Topic
Ginkgo biloba and Cashew Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Neuroprotective Herbs Associated with Parkinson’s and Alzheimer’s Disease

Anamaria POP, Claudia Paşca, Georgiana Smaranda Marțiș, Rodica Ana Ungur et al.
Nutrients
Ginkgo biloba and Cashew Applications
article

Neuroprotective Herbs Associated with Parkinson’s and Alzheimer’s Disease

Anamaria POP, Claudia Paşca, Georgiana Smaranda Marțiș, Rodica Ana Ungur, Ileana Monica Borda, Evelina Maria Bordean
article en

Abstract

There is currently no treatment for Parkinson's (PD) and Alzheimer's (AD) diseases, and medications that target the blockage of amyloid plaque cascades appear to be the most promising for preventing these diseases. However, it is believed that consuming natural antioxidants, particularly phytochemicals such as phenolic compounds, may help the treatment process for neurodegenerative illnesses. Phenolic substances such as phenolic acids, polyphenols, and flavonoids have been shown to have antioxidant properties in plants and are thought to have a similar impact in humans. This review provides an analysis of the current landscape of PD and AD pathophysiology, paying particular attention to phytochemical-based therapeutic, preventive, and management strategies using disclosed herb candidates in in vivo/vitro studies. We also highlight the herb-derived components that have recently been identified for their effects in the treatment of PD/AD to provide a review and perspectives for the development of the next generation of drugs and preparations for the treatment of PD/AD.

NutrientsVol. 18(3)
Technical University of Cluj-Napoca (RO), Iuliu Hațieganu University of Medicine and Pharmacy (RO), University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca (RO)
Good health and well-being
Openalex Percentile: Top 74%
Ginkgo biloba and Cashew Applications
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