Features of the Semen Microbial Contamination and Its Interactive Influence on SIRT1 Expression and the Development of Antibiotic Resistance
The results of this study indicate a strong association between microbial contamination of semen, oxidative stress, and decreased SIRT1 expression. The growing resistance of bacteria to commonly used antibiotics was also confirmed, posing a challenge to the effectiveness of current sanitary protocols in artificial insemination. SIRT1 may serve as a sensitive biomarker of semen quality and infection presence, providing added value in bull fertility diagnostics.
Authors
- Elżbieta Gałęska (ORCID: https://orcid.org/0000-0001-9582-3859)
- Marko Samardžija (ORCID: https://orcid.org/0000-0003-0402-3173)
- Wojciech WITKIEWICZ
- Alicja Kowalczyk (ORCID: https://orcid.org/0000-0003-1908-2942)
- Marcjanna Wrzecińska (ORCID: https://orcid.org/0000-0002-3529-8404)
- M.F. Camina
- José Pedro Araújo
- Ewa Czerniawska‐Piątkowska
- Zbigniew Dobrzański
Institutions
- Animal Welfare Institute (US)
- West Pomeranian University of Technology in Szczecin (PL)
- University of Zagreb (HR)
- Universidade Politécnica de Viana do Castelo (PT)
- Universidade de Santiago de Compostela (ES)
- Wrocław University of Environmental and Life Sciences (PL)
- Łukasiewicz Research Network – PORT Polish Center for Technology Development (PL)
Publication Details
- Journal
- Andrology
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1111/andr.70186
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniwersytet Przyrodniczy we Wroclawiu