Proposal, Derivation, and External Validation of a Novel Geographic Atrophy Outcome Measure
In this prognostic study, results suggest that the novel GA outcome measure aligned with BCVA, a key functional outcome measure, by empirical weighting of concentric annuli. This provided a surrogate measure to track predicted functional decline objectively and more meaningfully than GA area.
Authors
- Tiarnán D L Keenan (ORCID: https://orcid.org/0000-0002-2253-1772)
- Souvick Mukherjee (ORCID: https://orcid.org/0000-0003-0748-8371)
- E Y Chew
- Emily Vance
- Jintong Hou
- Elvira Agrón
- Leon von der Emde
Institutions
- National Institutes of Health (US)
- University of Bonn (DE)
- University of Wisconsin–Madison (US)
- National Eye Institute (US)
Publication Details
- Journal
- JAMA Ophthalmology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1001/jamaophthalmol.2025.6002
- Primary Topic
- Ophthalmology and Visual Impairment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00