Significantly Decreased Progesterone Receptor Expression in Corded and Hyalinized Variant of Endometrioid Adenocarcinoma: A Potential Cause of Resistance to Progestin Treatment
Considering the usual high rate of complete remission with progestin treatment in patients with EAC, the high rate of persistent tumors in our case series suggests that CHEC may be intrinsically resistant to progestin treatment due to the lack of expression of PR in the CoES component.
Authors
- Uiree Jo (ORCID: https://orcid.org/0000-0001-6783-4016)
- Chang Ohk Sung
- Bong-Hee Park
- Kyu-Rae Kim
Institutions
- Ulsan College (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Seoul Medical Center (KR)
Publication Details
- Journal
- Pathobiology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1159/000549857
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00