Investigation of the drug release modifying property of Pentadesma butyracea gum in diclofenac sodium matrix tablets
A matrix system comprising 15%w/w P. butyracea gum and ≥ 20%w/w xanthan gum effectively extended the release of diclofenac sodium over 24 hours, demonstrating its potential application in extended-release formulations.
Authors
- Frederick William Akuffo Owusu (ORCID: https://orcid.org/0000-0003-2674-6217)
- Raphael Johnson (ORCID: https://orcid.org/0000-0003-4829-2447)
- Mary-Ann Archer (ORCID: https://orcid.org/0000-0002-0834-1518)
- Isaac Yaw Attah
- Samuel Lugrie Kipo (ORCID: https://orcid.org/0000-0001-6643-6614)
- Prince George Jnr Acquah
- Kwabena Ofori-Kwakye
Institutions
- University of Cape Coast (GH)
- Kwame Nkrumah University of Science and Technology (GH)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1371/journal.pone.0341668
- Citations
- 1
- Primary Topic
- Polysaccharides Composition and Applications
- Type
- article
- Field-Weighted Citation Impact
- 30.02
Funders
- Kwame Nkrumah University of Science and Technology