Gut-kidney-brain axis and daytime sleepiness in Parkinson's disease and chronic kidney disease: an expert narrative review
Targeting the gut-kidney-brain axis holds substantial promise for managing EDS, supported by moderate-certainty evidence for BBPI-based approaches. However, clinical translation necessitates personalized intervention frameworks and validation through large-scale multicenter trials.
Authors
- Shanshan Yang (ORCID: https://orcid.org/0000-0002-0997-7251)
- Canmin Zhu
- Na Gong
- Ke Cheng
- Xinyue Wang
- Shihong Xiong
Institutions
- Integrated Chinese Medicine (China) (HK)
- The First People's Hospital of Jiangxia District (CN)
- Wuhan University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fnagi.2025.1728664
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wuhan University
- Wuhan University of Science and Technology