Endometrial Mixed and Mixed-Feature Carcinomas: Small Cohort Clinicopathologic and Molecular Studies

Mixed and mixed-feature carcinomas share origins with pure endometrial serous and endometrioid carcinoma subtypes but exhibit distinct molecular alterations. These findings highlight the importance of molecular subtyping for diagnosis and treatment planning. Future research could focus on larger cohorts and targeted sequencing to better understand the pathogenesis of mixed and mixed-feature carcinomas in order to refine therapeutic strategies.

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Publication Details

Journal
Cancers
Published
2026-01-29
DOI
https://doi.org/10.3390/cancers18030440
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Endometrial Mixed and Mixed-Feature Carcinomas: Small Cohort Clinicopathologic and Molecular Studies

Tamara Kalir, Brett Baskovich, Rachel Brody, Olga Lukatskaya et al.
Cancers
Endometrial and Cervical Cancer Treatments
article

Endometrial Mixed and Mixed-Feature Carcinomas: Small Cohort Clinicopathologic and Molecular Studies

Tamara Kalir, Brett Baskovich, Rachel Brody, Olga Lukatskaya, Yayoi Kinoshita, Stephanie V. Blank, Mona Saleh
article en

Abstract

Mixed and mixed-feature carcinomas share origins with pure endometrial serous and endometrioid carcinoma subtypes but exhibit distinct molecular alterations. These findings highlight the importance of molecular subtyping for diagnosis and treatment planning. Future research could focus on larger cohorts and targeted sequencing to better understand the pathogenesis of mixed and mixed-feature carcinomas in order to refine therapeutic strategies.

CancersVol. 18(3)
Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 75%
Endometrial and Cervical Cancer Treatments
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