A prospective study on the impact of high-grade atrioventricular block (HAVB) on outcomes in patients with acute myocardial infarction (AMI)

Background: Contemporary data on the impact of high-grade atrioventricular blocks (HAVB) in acute myocardial infarction (AMI) are scarce. Therefore, we investigated this in the Swiss national AMI registry (AMIS Plus) cohort. Methods: We included all AMI patients enrolled from January 2005 to September 2024 with available ECG information. Primary outcome was in-hospital mortality; secondary outcomes included in-hospital major adverse cardiac or cerebrovascular events (MACCE) defined as cardiogenic shock, stroke, re-infarction or death. Conclusion: HAVB in AMI was associated with high in-hospital mortality, especially in anterior AMI or if occurring during hospitalisation. Permanent pacemaker implantation was more frequent in the setting of NSTEMI and among patients developing HAVB during hospital stay.