Identification and comparative genomic analysis of prophage sequences and CRISPR‒Cas immunity in Methylococcus genomes: insights into industrial methane bioconversion
These findings considerably advance the current understanding of the genetic diversity and biological properties of prophages infecting Methylococcus species, underscoring the importance of holistic approaches for the detection and analysis of these elements. Our findings underscore the need for routine prophage monitoring in industrial methanotrophic consortia, with the pipeline established here serving as a foundational framework for future refinement and industrial adaptation.
Authors
- A. V. Rezaykin (ORCID: https://orcid.org/0000-0002-8665-5299)
- Irina Gennadievna Nizovtseva (ORCID: https://orcid.org/0000-0002-7766-7351)
- Maksim Zakhartsev (ORCID: https://orcid.org/0000-0002-7973-9902)
- Dmitrii Chernushkin (ORCID: https://orcid.org/0000-0002-4822-6055)
- Alina Chigireva
- I. O. Starodumov
- Aleksandra Korenskaia
Institutions
- Ural Federal University (RU)
- Schott (Germany) (DE)
- Ural State Medical University (RU)
- Institute of Medical Cell Technologies (RU)
- Bernstein Center for Computational Neuroscience Tübingen (DE)
- Federal Research Centre «Fundamentals of Biotechnology» of the Russian Academy of Sciences (RU)
- BioTez (Germany) (DE)
- Friedrich Schiller University Jena (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Biotechnology for Biofuels and Bioproducts
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1186/s13068-026-02738-6
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00