A liver function test pathway significantly increases the early detection of chronic liver disease and cirrhosis
In this long-term, population-level evaluation, reflex AST:ALT testing increased cirrhosis detection in both regions and produced a short-term rise in chronic liver disease (including cirrhosis) diagnoses one region, strengthening the evidence of the pathway's effect on cirrhosis detection. Further study is warranted to understand regional variation.
Authors
- Ashley Akbari
- Aled Davies (ORCID: https://orcid.org/0000-0001-7768-7590)
- Jun Gao (ORCID: https://orcid.org/0009-0007-1487-2861)
- Haroon Ahmed
- Rebecca Cannings-John
- Thomas Peter I. Pembroke
Institutions
- University Hospital of Wales (GB)
- Swansea University (GB)
- Cardiff University (GB)
- Cardiff Metropolitan University (GB)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1097/hc9.0000000000000887
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00