Universal Newborn Screening for Congenital Cytomegalovirus Using Dried Blood Spot Specimens

In this diagnostic study, early identification of cCMV allowed newborns to be evaluated, which provided an opportunity for improved outcomes. Although the intent of the screening was to detect cCMV, a sizeable minority of cases identified had postnatally acquired CMV infections. Further studies that incorporate long-term data are needed to better understand the impact of cCMV identification among newborns with asymptomatic infection.

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Publication Details

Journal
JAMA Network Open
Published
2026-01-29
DOI
https://doi.org/10.1001/jamanetworkopen.2025.54518
Citations
1
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
31.52
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Universal Newborn Screening for Congenital Cytomegalovirus Using Dried Blood Spot Specimens

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JAMA Network Open
Cytomegalovirus and herpesvirus research
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Universal Newborn Screening for Congenital Cytomegalovirus Using Dried Blood Spot Specimens

Lisa DiAntonio, Christine M. Salvatore, Jennifer L. Nayak, Sharon Nachman, Patricia DeLaMora, Stephanie P. Ungar, Virginia Sack, Mark D. Hicar, Sarah Bradley, Michael T. Quinn, Julia A Piwoz, Melissa B. Pearce, Charity McManaman, Norma P. Tavakoli, Leonard B. Weiner, Andrew S Handel, Minnie John, Sunil K. Sood, Jency M. Daniel, Ifeyinwa Ojukwu, Sheila M. Nolan, Saul Hymes, Christopher J. Brandon, Denise M. Kay, Danielle Daniels, Alyssa Giacinto, Gitanjali Rebello, Lequela Steen, Geoffrey A. Weinberg, Carlos Saavedra-Matiz, Marc St-Pierre, Michele Caggana
article en
1 citations

Abstract

In this diagnostic study, early identification of cCMV allowed newborns to be evaluated, which provided an opportunity for improved outcomes. Although the intent of the screening was to detect cCMV, a sizeable minority of cases identified had postnatally acquired CMV infections. Further studies that incorporate long-term data are needed to better understand the impact of cCMV identification among newborns with asymptomatic infection.

JAMA Network OpenVol. 9(1)
Albany State University (US), New York State Department of Health (US), Wadsworth Center (US), NewYork–Presbyterian Hospital (US), New York Medical College (US), SUNY Upstate Medical University (US), Cornell University (US), University at Albany, State University of New York (US), Stony Brook School (US), Cohen Children's Medical Center (US), Golisano Children's Hospital (US), Children's Hospital at Montefiore (US), Jacobs Institute (US), New York University (US), Stony Brook University (US), Albany Medical Center Hospital (US)
Good health and well-being
Openalex Percentile: Top 1%
Cytomegalovirus and herpesvirus research
31.52
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