Morphological and microstructural brain changes induced by cognitive training among non-demented participants: a systematic review and meta-analysis

Training groups showed no significant morphological or microstructural modifications compared to control conditions. The current results of objective markers are not powerful enough to recommend cognitive training as a preventive method. Future research should focus on proper randomization, elimination of baseline differences and use standardized techniques. The review was pre-registered with PROSPERO (ID: CRD42023485440).

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Publication Details

Journal
NeuroImage
Published
2026-01-30
DOI
https://doi.org/10.1016/j.neuroimage.2026.121767
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Morphological and microstructural brain changes induced by cognitive training among non-demented participants: a systematic review and meta-analysis

Tímea Lázár, Szabolcs Kéri, Eszter Radics, Péter Hegyi et al.
NeuroImage
Dementia and Cognitive Impairment Research
article

Morphological and microstructural brain changes induced by cognitive training among non-demented participants: a systematic review and meta-analysis

Tímea Lázár, Szabolcs Kéri, Eszter Radics, Péter Hegyi, Marie Anne Engh, András Attila Horváth, Marah Qussous, Szilvia Kiss-Dala
article en

Abstract

Training groups showed no significant morphological or microstructural modifications compared to control conditions. The current results of objective markers are not powerful enough to recommend cognitive training as a preventive method. Future research should focus on proper randomization, elimination of baseline differences and use standardized techniques. The review was pre-registered with PROSPERO (ID: CRD42023485440).

NeuroImageVol. 328
Semmelweis University (HU), University of Szeged (HU)
Openalex Percentile: Top 75%
Dementia and Cognitive Impairment Research
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