Analysis of comorbid characteristics, molecular mechanisms between mild cognitive impairment and Alzheimer’s disease with interventions in a community-based population in Shanghai

MCI patients in the community are at high risk of AD, and their comorbidity characteristics are affected by multidimensional lifestyle and psychological factors. Boldine and piceatannol may be potential natural compounds for the intervention of cognitive impairment. The results of this study can provide a theoretical basis for the early prevention and precise intervention of cognitive impairment in the community.