Genomic characterization of colistin- and carbapenem-resistant <i>Pseudomonas aeruginosa</i> ST1560 from Guanabara Bay, Brazil
The P. aeruginosa ST1560 displays a complex multidrug resistance profile, including resistance to both colistin and carbapenems. This phenotype appears to be mediated by a combination of acquired resistance genes and chromosomal mechanisms. The localization of blaKPC-2 within a mobile genetic element underscores the risk of dissemination in aquatic environments.
Authors
- Rodolfo Paranhos
- Kaylanne Montenegro
- Mariana Magaldi
- Maiara Lopes-carvalho
- Hosana Dau Ferreira de Souza (ORCID: https://orcid.org/0000-0002-0221-1333)
- Hugo Sérgio Oliveira Santos
- Alexander Machado Cardoso
- Maysa Mandetta Clementino
- Kayo Bianco
- Vinicius Carneiro Assunção
- Andressa Silva Gonçalves-Britto
- Thereza Cristina Costa Vianna
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade do Estado do Rio de Janeiro (BR)
- Czech Academy of Sciences, Institute of Biophysics (CZ)
- National Institute of Quality (PE)
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (BR)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1093/jambio/lxag035
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00