Depression mediated sleep disturbances and cognitive decline in Parkinson’s disease patient
Divergent neurobehavioral mechanisms underlie sleep-related cognitive decline in PD: daytime sleepiness operates through mood dysregulation, while rapid eye movement sleep disorder involves additional direct neural insult. Interventions targeting these pathways may require distinct strategies.
Authors
- Huashuo Zhao (ORCID: https://orcid.org/0000-0002-6592-1201)
- Yanan Sun (ORCID: https://orcid.org/0000-0003-4940-3743)
- QiuShuang Wang
- ZiXuan Zhao
- Sizhao Li
Institutions
- Nanjing University of Chinese Medicine (CN)
- Xuzhou Medical College (CN)
- Zhengzhou University (CN)
- Cixian People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fnins.2026.1722979
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- Sanofi
- Biogen
- Teva Pharmaceutical Industries
- Celgene
- Jazz Pharmaceuticals
- Neurocrine Biosciences
- Verily Life Sciences
- Voyager Therapeutics
- National Natural Science Foundation of China
- Servier
- H. Lundbeck A/S
- Sun Pharma
- Genentech
- Allergan
- Avid Radiopharmaceuticals