Sex-Based Differences in the Effect of Short Dual Antiplatelet Therapy Followed by Prasugrel Monotherapy in High-Bleeding-Risk Patients After Percutaneous Coronary Intervention

Background: In patients at high bleeding risk (HBR), short dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) reduces bleeding without increasing ischemic events. However, the sex-based differences in the effects of short DAPT strategy followed by prasugrel monotherapy compared with conventional DAPT strategy remain unclear.

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Publication Details

Journal
Circulation Reports
Published
2026-01-29
DOI
https://doi.org/10.1253/circrep.cr-25-0298
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Sex-Based Differences in the Effect of Short Dual Antiplatelet Therapy Followed by Prasugrel Monotherapy in High-Bleeding-Risk Patients After Percutaneous Coronary Intervention

Anna Tsutsui, Satoru Abe, Go Kato, Ken Kozuma et al.
Circulation Reports
Antiplatelet Therapy and Cardiovascular Diseases
article

Sex-Based Differences in the Effect of Short Dual Antiplatelet Therapy Followed by Prasugrel Monotherapy in High-Bleeding-Risk Patients After Percutaneous Coronary Intervention

Anna Tsutsui, Satoru Abe, Go Kato, Ken Kozuma, Masayuki Fukuzawa, Raisuke Iijima, Norihiro Kogame, Yoshitaka Murakami, Masato Nakamura, Yoshihisa Nakagawa
article en

Abstract

Background: In patients at high bleeding risk (HBR), short dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) reduces bleeding without increasing ischemic events. However, the sex-based differences in the effects of short DAPT strategy followed by prasugrel monotherapy compared with conventional DAPT strategy remain unclear.

Circulation Reports
Toho University (JP), Shiga University of Medical Science (JP), Toho University Ohashi Medical Center (JP), Daiichi Sankyo (United Kingdom) (GB), Tokyo Rosai Hospital (JP), Teikyo University (JP)
Forskningsrådet om Hälsa, Arbetsliv och Välfärd, Daiichi Sankyo Europe
Openalex Percentile: Top 75%
Antiplatelet Therapy and Cardiovascular Diseases
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