Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials
There is insufficient evidence to support a significant efficacy of FMT on depressive symptoms, but subgroup analyses suggest that FMT may have a better antidepressant effect in the population with confirmed depression, and therefore more randomized controlled trials are necessary to validate the association between FMT and depressive symptoms.
Authors
- Yuewen Liu (ORCID: https://orcid.org/0000-0003-1398-3096)
- Shirui Liu
- Xing Yu (ORCID: https://orcid.org/0000-0002-0143-4084)
- C Koo Seen Lin
- Jiamin Fu (ORCID: https://orcid.org/0000-0002-7700-9615)
- Yuchi Zhang (ORCID: https://orcid.org/0000-0001-8083-8935)
- Ziyi Zhou (ORCID: https://orcid.org/0009-0009-0367-7256)
- Jing Gao
- Ruiting Liang
- Jinwan Zhao
- Zhixin Zhang
- Hongyun Zhou
- Xiaoyu Chen
- Peipei Han
- Qi Guo
- Ming Lan
Institutions
- Fujian Medical University (CN)
- Tianjin University of Sport (CN)
- Shanghai University of Medicine and Health Sciences (CN)
- Community Health Center (US)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fpsyt.2025.1629290
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 22.24
Funders
- Science and Technology Commission of Shanghai Municipality