Previable preterm premature rupture of membranes (before 24 weeks gestation): Pregnancy and neonatal outcomes

• This large single-center study demonstrates improved neonatal outcomes following previable PPROM, likely reflecting in perinatal practices, compared to the historical cohort. • Short latency between previable PPROM and delivery, as well as lower gestational age at birth, were identified as independent risk factors for death or severe morbidity. • The study provides updated, real-world data to guide parental counseling and clinical decision-making regarding previable PPROM.

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Publication Details

Journal
European Journal of Pediatrics
Published
2026-01-30
DOI
https://doi.org/10.1007/s00431-026-06773-1
Primary Topic
Preterm Birth and Chorioamnionitis
Type
article
Field-Weighted Citation Impact
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article

Previable preterm premature rupture of membranes (before 24 weeks gestation): Pregnancy and neonatal outcomes

Kévin Le Duc, V. Houfflin‐Debarge, Mohamed Riadh Boukhris, Audrey COSSART et al.
European Journal of Pediatrics
Preterm Birth and Chorioamnionitis
article

Previable preterm premature rupture of membranes (before 24 weeks gestation): Pregnancy and neonatal outcomes

Kévin Le Duc, V. Houfflin‐Debarge, Mohamed Riadh Boukhris, Audrey COSSART, Louise Ghesquiere, Laurent Storme
article en

Abstract

• This large single-center study demonstrates improved neonatal outcomes following previable PPROM, likely reflecting in perinatal practices, compared to the historical cohort. • Short latency between previable PPROM and delivery, as well as lower gestational age at birth, were identified as independent risk factors for death or severe morbidity. • The study provides updated, real-world data to guide parental counseling and clinical decision-making regarding previable PPROM.

European Journal of PediatricsVol. 185(2)
Université de Lille (FR), Centre Hospitalier Universitaire de Lille (FR), Hôpital Jeanne de Flandre (FR)
Good health and well-being
Openalex Percentile: Top 74%
Preterm Birth and Chorioamnionitis
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