Integrated Single-Cell and Bulk RNA Sequencing Identifies SERPING1 as a Biomarker of Immune Infiltration and Prognosis in Triple-Negative Breast Cancer
<i>SERPING1</i> contributes to enhanced immune cell infiltration, desirable immunotherapy response, and improved prognosis. It thus can be utilized as a promising biomarker for immune infiltration and prognosis. These findings provide novel insights into TME-related immune regulation and may inform strategies to enhance immunotherapy efficacy in TNBC.
Authors
- Hanyu Zhang (ORCID: https://orcid.org/0000-0003-2393-3906)
- Anbang Hu (ORCID: https://orcid.org/0000-0003-0432-8081)
- Yuhang Shang
- Mingcui Li (ORCID: https://orcid.org/0000-0002-9413-7723)
- Baoliang Guo
- Zhiyuan Rong
- Runze Guo
- Xi’ao Wang
- Yunqiang Duan (ORCID: https://orcid.org/0000-0003-0143-9368)
- Yanling Li (ORCID: https://orcid.org/0000-0002-7764-3819)
- Zhengbo Fang
- Jiangwei Liu (ORCID: https://orcid.org/0000-0002-7652-9379)
- Yuehua Chen (ORCID: https://orcid.org/0009-0006-1343-7449)
- Yuyu Liu (ORCID: https://orcid.org/0000-0002-4814-8616)
- Yuanhao Ji
- Weilun Cheng
- Yunyi Ji
- Delong Cui
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2026-01-22
- DOI
- https://doi.org/10.31083/fbl47089
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00