A Virtual Trial to Identify Cardiovascular Biomarkers for Differentiating Diabetic and Hypertensive Kidney Disease
This modeling work suggests that cardiovascular biomarkers can assist in differentiating DKD and HKD, and proposes specific hypotheses that form a strong rationale for targeted clinical trials. If confirmed, these methods could enable non-invasive assessment of renal vascular alterations associated with DKD and HKD, reducing reliance on kidney biopsies for diagnostic evaluation.
Authors
- Ivan Benemerito (ORCID: https://orcid.org/0000-0002-4942-7852)
- Steven Sourbron
- Alberto Marzo
- Ning Wang
Institutions
- Insigneo (GB)
- University of Sheffield (GB)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1007/s10439-026-03983-4
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Engineering and Physical Sciences Research Council