Canadian real-world evidence: observational 24-week outcomes for health care practitioner authorized cannabis

At Week 24, outcomes in chronic pain, anxiety, depression, and quality of life improved. Although 85% of patients in our study had an MC indication for pain, no outcomes met their minimal clinically significant thresholds at Week 24. These observations align with existing evidence, yet there remains some discrepancies in the current literature. Our findings highlight the need for future studies to characterize MC administration, dose, and specific product relationships.

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Publication Details

Journal
Canadian Journal of Pain
Published
2026-01-29
DOI
https://doi.org/10.1080/24740527.2025.2593253
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Canadian real-world evidence: observational 24-week outcomes for health care practitioner authorized cannabis

CAROLINA LANDOLT, Praveen Ganty, Leeping Tao, Alexander Huang et al.
Canadian Journal of Pain
Cannabis and Cannabinoid Research
article

Canadian real-world evidence: observational 24-week outcomes for health care practitioner authorized cannabis

CAROLINA LANDOLT, Praveen Ganty, Leeping Tao, Alexander Huang, Hance Clarke, Joseph Fiorellino, Aly Lakhani, Peter L. Carlen, Mandeep Singh, G. Gabriel, Sonalben Thaker, Pope Elena, Henry Cortés Pradilla, Calvin Diep, Keriann Tingling, Kiritpaul Nandra, Rasheeda Darville, Hai Yu, Peter Chung Tai, Brian Yang, Ken Weisbrod, Ted Jackson
article en

Abstract

At Week 24, outcomes in chronic pain, anxiety, depression, and quality of life improved. Although 85% of patients in our study had an MC indication for pain, no outcomes met their minimal clinically significant thresholds at Week 24. These observations align with existing evidence, yet there remains some discrepancies in the current literature. Our findings highlight the need for future studies to characterize MC administration, dose, and specific product relationships.

Canadian Journal of PainVol. 10(1)
University Health Network (CA), University of Calgary (CA), University of Toronto (CA), Toronto Western Hospital (CA), Western General Hospital (GB), Telus (Canada) (CA), Hospital for Sick Children (CA), Toronto General Hospital (CA), Georgetown Hospital (CA), Health Net (US), Pain Management Institute (US), Western Research Institute (US), Newmarket Hospital (GB), Hospital la Serena (CL), Headwaters Health Care Centre (CA)
Openalex Percentile: Top 73%
Cannabis and Cannabinoid Research
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Canadian real-world evidence: observational 24-week outcomes for health care practitioner authorized cannabis — CAROLINA LANDOLT, Praveen Ganty, et al. · Canadian Journal of Pain (2026) | TGRS Research Map | TGRS