Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling

Dacryops involves reactive ductular ectasia secondary to inflammation, resulting in increased MMPs, fibrosis, and loss of the periductal neural network. The cyst fluid is rich in apolipoproteins, immunoglobulins, and complement factors. Future research could focus on the lipidomics of the cyst fluid.

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Publication Details

Journal
The Ocular Surface
Published
2026-01-30
DOI
https://doi.org/10.1016/j.jtos.2026.01.007
Primary Topic
Nasolacrimal Duct Obstruction Treatments
Type
article
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article

Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling

Swati Singh
The Ocular Surface
Nasolacrimal Duct Obstruction Treatments
article

Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling

Swati Singh
article en

Abstract

Dacryops involves reactive ductular ectasia secondary to inflammation, resulting in increased MMPs, fibrosis, and loss of the periductal neural network. The cyst fluid is rich in apolipoproteins, immunoglobulins, and complement factors. Future research could focus on the lipidomics of the cyst fluid.

The Ocular SurfaceVol. 40
L V Prasad Eye Institute (IN)
Openalex Percentile: Top 75%
Nasolacrimal Duct Obstruction Treatments
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Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling — Swati Singh · The Ocular Surface (2026) | TGRS Research Map | TGRS