Comparing short- and long-term survivors in metastatic pancreatic cancer: Insights into patient and disease profiles impacting systemic therapy outcomes

Patient- and tumour-specific characteristics strongly influence survival in mPAC patients receiving systemic therapy. These findings can support a more detailed risk stratification at diagnosis to optimise treatment selection, avoid both over- and undertreatment, and align care with individual patient expectations and values for more personalised treatment strategies.

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Publication Details

Journal
European Journal of Cancer
Published
2026-01-29
DOI
https://doi.org/10.1016/j.ejca.2026.116263
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
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article

Comparing short- and long-term survivors in metastatic pancreatic cancer: Insights into patient and disease profiles impacting systemic therapy outcomes

Liselot Valkenburg‐van Iersel, Judith de Vos‐Geelen, Merlijn U.J.E. Graus, Lydia GM van der Geest et al.
European Journal of Cancer
Pancreatic and Hepatic Oncology Research
article

Comparing short- and long-term survivors in metastatic pancreatic cancer: Insights into patient and disease profiles impacting systemic therapy outcomes

Liselot Valkenburg‐van Iersel, Judith de Vos‐Geelen, Merlijn U.J.E. Graus, Lydia GM van der Geest, Aniek E. van Diepen, Jeanin E. van Hooft, Marjolein Y.V. Homs, Miriam L Wumkes, Ignace H.J.T. de Hingh, Thijmen Broekman, Johanna W. Wilmink, Casper W.F. van Eijck
article en

Abstract

Patient- and tumour-specific characteristics strongly influence survival in mPAC patients receiving systemic therapy. These findings can support a more detailed risk stratification at diagnosis to optimise treatment selection, avoid both over- and undertreatment, and align care with individual patient expectations and values for more personalised treatment strategies.

European Journal of CancerVol. 236
Radboud University Nijmegen (NL), Leiden University Medical Center (NL), Maastricht University Medical Centre (NL), Catharina Ziekenhuis (NL), Erasmus MC (NL), Netherlands Comprehensive Cancer Organisation (NL), Erasmus MC Cancer Institute (NL), Amsterdam University Medical Centers (NL), Jeroen Bosch Ziekenhuis (NL), Amsterdam University of Applied Sciences (NL), University of Amsterdam (NL), Erasmus University Rotterdam (NL)
Good health and well-being
Openalex Percentile: Top 74%
Pancreatic and Hepatic Oncology Research
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Comparing short- and long-term survivors in metastatic pancreatic cancer: Insights into patient and disease profiles impacting systemic therapy outcomes — Liselot Valkenburg‐van Iersel, Judith de Vos‐Geelen, et al. · European Journal of Cancer (2026) | TGRS Research Map | TGRS