The Icelandic Mutation in the Murine APP Gene, mAPPA673T, on Amyloid-β Plaque Burden in the 5×FAD Alzheimer Model
The mAPP<sup>A673T</sup> mutation has the potential to modify Aβ pathology in 5×FAD mice at the age of 6 months.
Authors
- Karima Schwab (ORCID: https://orcid.org/0000-0001-7063-7136)
- Anne Anschuetz (ORCID: https://orcid.org/0009-0002-9287-8461)
- Thomas Vorley
- Renny Listyono
- Gernot Riedel
- Bettina Platt
- Charles R. Harrington
Institutions
- University of Aberdeen (GB)
- TauRx (United Kingdom) (GB)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2026-01-22
- DOI
- https://doi.org/10.31083/jin48581
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- TauRx Pharmaceuticals