MORC–ALKBH1 antagonism shapes three‐dimensional gene regulation in rice

This commentary highlights how antagonistic actions between MORC proteins and the DNA demethylase ALKBH1 shape three-dimensional chromatin organization in rice. By balancing gene silencing and activation at stress-responsive loci, this mechanism provides insights into chromatin regulation and offers potential applications for developing stress-resilient crop varieties through epigenomic breeding.

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Publication Details

Journal
Journal of Integrative Plant Biology
Published
2026-01-28
DOI
https://doi.org/10.1111/jipb.70163
Primary Topic
Plant Molecular Biology Research
Type
article
Field-Weighted Citation Impact
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article

MORC–ALKBH1 antagonism shapes three‐dimensional gene regulation in rice

W. Li, Frédéric Pontvianne, Leeza Tariq, Muhammad Fahad
Journal of Integrative Plant Biology
Plant Molecular Biology Research
article

MORC–ALKBH1 antagonism shapes three‐dimensional gene regulation in rice

W. Li, Frédéric Pontvianne, Leeza Tariq, Muhammad Fahad
article en

Abstract

This commentary highlights how antagonistic actions between MORC proteins and the DNA demethylase ALKBH1 shape three-dimensional chromatin organization in rice. By balancing gene silencing and activation at stress-responsive loci, this mechanism provides insights into chromatin regulation and offers potential applications for developing stress-resilient crop varieties through epigenomic breeding.

Journal of Integrative Plant Biology
Centre National de la Recherche Scientifique (FR), Université de Perpignan (FR), ZheJiang Academy of Agricultural Sciences (CN), Laboratoire Génome et Développement des Plantes (FR), China National Rice Research Institute (CN), Zhejiang University (CN)
Zero hunger
Openalex Percentile: Top 74%
Plant Molecular Biology Research
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