4A tetrahedron system: a synergistic framework for panvascular intervention empowered by flexible electronics

Abstract This review introduces the “4 A Tetrahedron System” (Assessment, Assistance, Aftercare, AI-retrofit) as a synergistic framework for panvascular intervention empowered by flexible electronics. Central to this is the novel concept of “suitcordance”—short-term suitability and long-term concordance. By integrating flexible sensors, navigation tools, and AI algorithms, this framework establishes a closed-loop data ecosystem, driving a transition toward intelligent, full-cycle disease management.