STC2 promotes anoikis resistance by modulating TGIF1 mRNA stability in colorectal cancer
Our findings suggest that STC2 promotes anoikis resistance in CRC by regulating TGIF1 mRNA stability. STC2 may serve as a potential therapeutic target and prognostic biomarker for colorectal cancer.
Authors
- Jie Cheng (ORCID: https://orcid.org/0000-0002-2452-6328)
- Fan Hu (ORCID: https://orcid.org/0000-0002-0522-392X)
- Jun Lin
- Qiuming He
- Zheyu Ding
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Central Hospital of Wuhan (CN)
- Hubei Cancer Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2026-01-29
- DOI
- https://doi.org/10.3389/fcell.2025.1695361
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00