MicroRNAs as potential prognostic biomarkers in acute lymphoblastic leukemia: a systematic review, meta-analysis, and bioinformatics study
These findings support miRNAs as valuable prognostic biomarkers for ALL with potential for personalized therapy. The context-dependent role of these miRNAs highlights the need for confirmation through large, multicenter trials. The constructed ceRNA network provides useful insights into their regulatory mechanisms, opening new directions for therapeutic strategies.
Authors
- Najmeh Salehi (ORCID: https://orcid.org/0000-0002-7337-4404)
- Samaneh Toutounchian (ORCID: https://orcid.org/0000-0002-1975-2697)
- Parmida Bagheri
- Zahra Salehi (ORCID: https://orcid.org/0000-0002-0839-2729)
- Kasra Izadpanahi
- Kiyarash Behboodi
- Fatemeh Mohagheghian
- Mona Alinejadfard
- Maedeh Mohaghegh
- Zahra Eghbali
Institutions
- University of Tehran (IR)
- Stem Cell Technology Research Center (IR)
- Institute for Research in Fundamental Sciences (IR)
- Shahid Beheshti University (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Systematic Reviews
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1186/s13643-026-03083-3
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00