Retrospective analysis of neurofilament-light chain in patients with inflammatory bowel disease – A pilot study
A slower age-dependent increase in serological NfL levels was found in Crohn's disease patients compared to control subjects. Larger studies assessing additional markers of neurodegeneration may be instrumental in addressing this question in the future.
Authors
- Moritz Middelhoff (ORCID: https://orcid.org/0000-0001-8425-3985)
- David Schult (ORCID: https://orcid.org/0000-0002-3022-799X)
- Paul Lingor
- Julius Shakhtour
- Nya Reinhardt
- Katja Steiger
- Roland M. Schmid
- Emily Feneberg
- Bernhard Haller
- Andreas Wolff
Institutions
- German Center for Neurodegenerative Diseases (DE)
- Munich Cluster for Systems Neurology (DE)
- Technical University of Munich (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-29
- DOI
- https://doi.org/10.1371/journal.pone.0340182
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft