Trigeminal somatosensory evoked potentials for intraoperative monitoring and prognostic prediction in microvascular decompression for trigeminal neuralgia: a prospective cohort study

The TSEP technique used in this study is simple to operate (only requiring puncture around the muscle groups near the puncture point), provides stable waveform results, and is convenient for intraoperative interpretation (only needing to observe changes in waveform amplitude). In addition, intraoperative monitoring of TNW2 amplitude change rate (≥60% indicates good prognosis) can provide real-time guidance during decompression and predict efficacy. The combination of hypertension, PTN duration ≥2.5 years, and TNW2 amplitude change rate <60% are independent risk factors for poor prognosis after MVD; patients with PTN who have hypertension, longer PTN duration, or TNW2 amplitude change rate <60% during microvascular decompression experience slower postoperative pain relief. The nomogram model based on TSEP waveforms, hypertension, and PTN duration has high accuracy and can individually assess recurrence risk, providing a tool for clinically identifying high-risk patients.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-01-29
DOI
https://doi.org/10.3389/fneur.2025.1693948
Primary Topic
Trigeminal Neuralgia and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Trigeminal somatosensory evoked potentials for intraoperative monitoring and prognostic prediction in microvascular decompression for trigeminal neuralgia: a prospective cohort study

Haipeng Xie, Wensong Wu, Zetong Bai, Kebin Zheng et al.
Frontiers in Neurology
Trigeminal Neuralgia and Treatments
article

Trigeminal somatosensory evoked potentials for intraoperative monitoring and prognostic prediction in microvascular decompression for trigeminal neuralgia: a prospective cohort study

Haipeng Xie, Wensong Wu, Zetong Bai, Kebin Zheng, Haiguang Liu, Yan Zhang, Yuanbo Hu, Yuanyuan Zhang, Yanbin Wang, Xichao Wen
article en

Abstract

The TSEP technique used in this study is simple to operate (only requiring puncture around the muscle groups near the puncture point), provides stable waveform results, and is convenient for intraoperative interpretation (only needing to observe changes in waveform amplitude). In addition, intraoperative monitoring of TNW2 amplitude change rate (≥60% indicates good prognosis) can provide real-time guidance during decompression and predict efficacy. The combination of hypertension, PTN duration ≥2.5 years, and TNW2 amplitude change rate <60% are independent risk factors for poor prognosis after MVD; patients with PTN who have hypertension, longer PTN duration, or TNW2 amplitude change rate <60% during microvascular decompression experience slower postoperative pain relief. The nomogram model based on TSEP waveforms, hypertension, and PTN duration has high accuracy and can individually assess recurrence risk, providing a tool for clinically identifying high-risk patients.

Frontiers in NeurologyVol. 16
Hebei Medical University (CN), TED University (TR), Affiliated Hospital of Hebei University (CN), Baoji City Central Hospital (CN), Hebei University (CN)
Natural Science Foundation of Hebei Province
No poverty
Openalex Percentile: Top 75%
Trigeminal Neuralgia and Treatments
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Trigeminal somatosensory evoked potentials for intraoperative monitoring and prognostic prediction in microvascular decompression for trigeminal neuralgia: a prospective cohort study — Haipeng Xie, Wensong Wu, et al. · Frontiers in Neurology (2026) | TGRS Research Map | TGRS