Association of <i>CYP2C19</i> gene single nucleotide polymorphisms (rs12248560 and rs4244285) with response to thalidomide in transfusion dependent β-thalassemia patients- a 12-months follow-up study
The findings suggest thalidomide as an effective option for TDT and highlight the potential role of CYP2C19 genetic variation in modulating treatment response.
Authors
- Inayat Ur Rahman (ORCID: https://orcid.org/0000-0002-0393-5819)
- Maryam Shahid
- Muhammad Tariq Masood Khan (ORCID: https://orcid.org/0000-0001-7841-7058)
- Sami Siraj
- Sher Afghan Khan
- Muhammad Tariq Humayun Khan
- Naseer Ahmed
- Amir Muhammad
- Abdus Saboor
- Shafiq Ahmad
Institutions
- Khyber Medical College (PK)
- Khyber Medical University (PK)
- Saidu Teaching Hospital (PK)
- Lady Reading Hospital (PK)
- University of Dental Medicine (MM)
- Plastic Surgery Hospital (CN)
- Aga Khan University (TZ)
- Behman Hospital (EG)
- Kamineni Institute of Dental Sciences (IN)
Publication Details
- Journal
- Pharmacogenomics
- Published
- 2025-12-12
- DOI
- https://doi.org/10.1080/14622416.2026.2622318
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00