Sex-specific associations between carotid plaque and bone mineral density in patients with type 2 diabetes: a retrospective cross-sectional study
Among patients with T2DM, carotid plaque was independently associated with worse osteoporosis category in women but not in men. These findings indicate sex-specific associations between carotid atherosclerosis and skeletal health; however, given the cross-sectional design and unavailable key confounders (e.g., lifestyle factors, central adiposity measures, medication patterns, and fracture outcomes), the results should be interpreted as associative and require confirmation in prospective studies.
Authors
- Qing Xue (ORCID: https://orcid.org/0000-0003-2946-9489)
- J. Chen
- Jingbo He
- Hao Qi
- Fei Gao
- Bing Liu
- Yue Liu
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1186/s13293-026-00830-y
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00