The mechanism regulating the cytotoxicity of γδ T cells activated by mycobacterium tuberculosis heat-resistant antigen based on RNA-seq analysis
Our findings demonstrated that Mtb-HAg enhances the cytolytic activity of γδ T cells and inhibits intracellular Mtb growth, with BTN3A1 playing a regulatory role in these processes.
Authors
- Zhi‐Gang Qian (ORCID: https://orcid.org/0000-0002-0133-0605)
- Sihang Dong
- Heng Zhang (ORCID: https://orcid.org/0000-0002-0103-2173)
- Baiqing Li
- Fangzheng Guo
- Yamin Song
- Tao Xu
- Hongtao Wang
- Xiaoyu Zhou
- Huiting Dai
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-28
- DOI
- https://doi.org/10.3389/fimmu.2026.1707304
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00