Ketogenic Strategies in Neonatal Hypoxic–Ischemic Encephalopathy—The Road to Opening Up: A Scoping Review

Ketogenic strategies represent a plausible, multimodal approach to targeting the metabolic and inflammatory sequelae of neonatal HIE. While current evidence is insufficient to support clinical implementation, this scoping review provides a hypothesis-generating framework to guide future translational research and the design of carefully controlled clinical trials in neonatal neurocritical care.

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Publication Details

Journal
Neurology International
Published
2026-01-28
DOI
https://doi.org/10.3390/neurolint18020024
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Ketogenic Strategies in Neonatal Hypoxic–Ischemic Encephalopathy—The Road to Opening Up: A Scoping Review

Annamaria Sapuppo, Vincenzo Sortino, Cristina Malaventura, S Fanaro et al.
Neurology International
Diet and metabolism studies
article

Ketogenic Strategies in Neonatal Hypoxic–Ischemic Encephalopathy—The Road to Opening Up: A Scoping Review

Annamaria Sapuppo, Vincenzo Sortino, Cristina Malaventura, S Fanaro, Agnese Suppiej, Elisa Ballardini, Falsaperla Raffaele, Aloise Martina
article en

Abstract

Ketogenic strategies represent a plausible, multimodal approach to targeting the metabolic and inflammatory sequelae of neonatal HIE. While current evidence is insufficient to support clinical implementation, this scoping review provides a hypothesis-generating framework to guide future translational research and the design of carefully controlled clinical trials in neonatal neurocritical care.

Neurology InternationalVol. 18(2)
University of Ferrara (IT), Università degli Studi di Enna Kore (IT), University of Catania (IT), Policlinico Universitario di Catania (IT), Institute for Biomedical Research and Innovation (IT)
Zero hunger
Openalex Percentile: Top 76%
Diet and metabolism studies
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Ketogenic Strategies in Neonatal Hypoxic–Ischemic Encephalopathy—The Road to Opening Up: A Scoping Review — Annamaria Sapuppo, Vincenzo Sortino, et al. · Neurology International (2026) | TGRS Research Map | TGRS