The beneficial effect of a multispecies probiotic intervention on quality of sleep – a randomized, double-blinded, placebo-controlled study

In conclusion, this well-powered RCT shows that the intervention with a multispecies probiotic improved quality of sleep beyond the effect of a placebo intervention, and that the modulation of the microbiome may therefore be of clinical benefit in alleviating sleep disturbances.

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Publication Details

Journal
Journal of Psychiatric Research
Published
2026-01-28
DOI
https://doi.org/10.1016/j.jpsychires.2026.01.040
Primary Topic
Gut microbiota and health
Type
article
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The beneficial effect of a multispecies probiotic intervention on quality of sleep – a randomized, double-blinded, placebo-controlled study

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The beneficial effect of a multispecies probiotic intervention on quality of sleep – a randomized, double-blinded, placebo-controlled study

Rosa Haller, J. Wagner-Skacel, Karin Schmid-Zalaudek, V. Stadlbauer, Tobias Madl, Angela Horvath, Hansjörg Habisch, Nandu Goaswami
article en

Abstract

In conclusion, this well-powered RCT shows that the intervention with a multispecies probiotic improved quality of sleep beyond the effect of a placebo intervention, and that the modulation of the microbiome may therefore be of clinical benefit in alleviating sleep disturbances.

Journal of Psychiatric ResearchVol. 195
Medical University of Graz (AT), BioTechMed-Graz (AT), Center For Biomarker Research In Medicine (AT)
Good health and well-being
Openalex Percentile: Top 75%
Gut microbiota and health
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