PSMA-guided management of recurrent post-prostatectomy patients: a sub-analysis of a prospective single-center study

PSMA-PET led to management changes in nearly one-third of post-prostatectomy recurrent PCa, notably affecting RT strategies and systemic therapy. Emerging evidence suggests that treatment intensification based on PSMA-PET findings may improve patient outcomes compared to de-intensified approaches. The impact on outcomes awaits validation from ongoing prospective randomized trials.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-29
DOI
https://doi.org/10.3389/fonc.2026.1764588
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

PSMA-guided management of recurrent post-prostatectomy patients: a sub-analysis of a prospective single-center study

Valeria Chiofalo, Umberto Ricardi, Erica Maria Cuffini, M. Levis et al.
Frontiers in Oncology
Prostate Cancer Treatment and Research
article

PSMA-guided management of recurrent post-prostatectomy patients: a sub-analysis of a prospective single-center study

Valeria Chiofalo, Umberto Ricardi, Erica Maria Cuffini, M. Levis, Cristiano Grossi, S Grimaldi, Guido ROVERA, R. Parise, Giuseppe Carlo Iorio, V. Richetto, Diego Bongiovanni, Paolo Gontero, F. Clot, Silvia Morbelli
article en

Abstract

PSMA-PET led to management changes in nearly one-third of post-prostatectomy recurrent PCa, notably affecting RT strategies and systemic therapy. Emerging evidence suggests that treatment intensification based on PSMA-PET findings may improve patient outcomes compared to de-intensified approaches. The impact on outcomes awaits validation from ongoing prospective randomized trials.

Frontiers in OncologyVol. 16
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT), Fondazione Ricerca Molinette (IT), Department of Medical Sciences (BY), University of Turin (IT)
Peace, Justice and strong institutions
Openalex Percentile: Top 75%
Prostate Cancer Treatment and Research
DOIOpen Access PDFOpenAlex
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PSMA-guided management of recurrent post-prostatectomy patients: a sub-analysis of a prospective single-center study — Valeria Chiofalo, Umberto Ricardi, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS